Operational and Financial Considerations

The Business of Precision

How Adaptive Radiotherapy Impacts Operations and Economics


Implementing Adaptive Radiotherapy in a clinical setting requires thoughtful operational, staffing and financial planning. While Adaptive Radiotherapy offers the potential for improved patient outcomes and more precise radiation delivery, its adoption involves integrating advanced imaging, treatment planning software, and adaptive workflows into existing radiation oncology infrastructure.

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Operational Excellence in Adaptive Radiotherapy


Adaptive Radiotherapy workflows are inherently more complex than conventional radiotherapy due to the need for frequent imaging, plan evaluation, replanning, and potential on-table plan adaption. Clinics must assess whether to implement online Adaptive Radiotherapy, where imaging and plan adaption occur while the patient is on the treatment table, or offline Adaptive Radiotherapy, which adjusts plans between treatment sessions. Online Adaptive Radiotherapy maximizes precision by accounting for daily anatomical changes, but it requires real-time imaging, AI-assisted contouring, and rapid treatment plan recalculation. Offline Adaptive Radiotherapy offers flexibility in centers where imaging resources are not co-located with treatment devices, and it can accommodate systematic changes occurring over weeks rather than days.

Staffing models also should evolve to support Adaptive Radiotherapy. Often radiation oncologists, medical physicists, and dosimetrists require additional training to manage adaptive planning, quality assurance, and workflow decision-making. AI-assisted auto-segmentation and automated plan evaluation tools can reduce the time burden, but human oversight remains critical to ensure safety and accuracy.

Balancing Cost, Capacity, and Care Quality

With projections indicating that an additional 6.5–8.4 million cancer patients may require radiotherapy by 2050, the demand for efficient, high-capacity treatment solutions is a pressing global health challenge.1 Advanced technologies that support hypofractionated schedules, delivering effective therapy in fewer sessions, can help meet this demand by reducing treatment times, lowering overall costs, and expanding patient access. Making these technologies more widely available should be a priority, as they improve operational efficiency for healthcare centers and make high-quality, precise care accessible to a growing patient population worldwide.

From a financial perspective, fewer treatment sessions can lead to significant cost savings for payers and patients. Insurers may see reduced expenditures, while patients benefit from lower co-pays, reduced transportation expenses, and decreased time away from work or family responsibilities. For hospitals and treatment centers, hypofractionated schedules reduce the number of treatment visits each patient requires. While the daily workload remains similar, over time this can lessen pressure on waiting lists, simplify scheduling, and provide more flexibility in how machines and staff are allocated.

Techniques such as intensity modulated RT (IMRT), stereotactic radiosurgery (SRS), or stereotactic body radiation therapy (SBRT) allow higher doses to be delivered safely per fraction. Optimizing total dose delivery and fractionation improves both patient safety and treatment efficiency. Additionally, cone beam CT (CBCT), performed with the patient in the treatment position, streamlines workflow by eliminating separate CT simulation sessions, offering greater convenience and operational efficiency.

Faster imaging and automated plan adjustments make daily or weekly adaption feasible without adding undue burden on clinical staff. This efficiency can translate into cost savings, increased patient capacity, and improved access to high-precision care.

By balancing operational efficiency with treatment quality, Adaptive Radiotherapy provides both clinical and financial value, enabling centers to deliver individualized, high-impact care while maximizing the return on investment in advanced technology. Ultimately, Adaptive Radiotherapy aligns clinical innovation with sustainable financial stewardship, benefiting the entire healthcare ecosystem.

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References

  1. Zhu H, Chua MLK, Chitapanarux I, et al. Global RT demands and corresponding RT-professional workforce requirements in 2022 and predicted to 2050: a population-based study. The Lancet Global Health, 2024;12(12), e1945 - e1953.